Molecular Formula of 2-Mercapto-5-methoxybenzimidazole: C8H8N2OS.

Appearance: An off-white to light yellowish-brown powder

CAS Number: 37052-78-1

• A: 10% Sodium Hydroxide: Should be clear
• B: Methanol: Should be clear

2-Mercapto-5-methoxybenzimidazole is a benzimidazole derivative where the molecular structure includes a methoxy group (-OCH3) at the fifth position and a mercapto group (-SH) at the second position on the benzimidazole ring. This compound is characterized by its distinct off-white to light yellowish-brown color and its specific solubility properties in different solvents.

When dissolved in a 10% sodium hydroxide solution, the solution should appear clear, indicating good solubility and no precipitation. Similarly, when dissolved in methanol, the solution should also be clear, demonstrating its solubility in organic solvents.

2-Mercapto-5-methoxybenzimidazole is a key intermediate in the synthesis of Omeprazole, a widely used proton pump inhibitor (PPI). Omeprazole is effective in reducing gastric acid secretion and is commonly prescribed for the treatment of various acid-related gastrointestinal conditions, such as:

Gastroesophageal Reflux Disease (GERD): Omeprazole helps manage and alleviate symptoms by reducing the amount of acid produced in the stomach.
Peptic Ulcers: It aids in healing ulcers in the stomach and duodenum by creating a less acidic environment.
Zollinger-Ellison Syndrome: This condition, characterized by excessive acid production, can be managed with Omeprazole to control acid levels and prevent complications.

2-Mercapto-5-methoxybenzimidazole, an important compound in the pharmaceutical industry for the production of Omeprazole. Its specific solubility characteristics and chemical structure make it a valuable intermediate in the synthesis of medications that manage and treat acid-related conditions.