Synonyms:
- O-Phenylene Thiourea;
- Phenylenethiourea;
- 1H-Benzimidazole-2-Thiol;
- 2-Benzimidazolinethione;
- 2-Thiobenzimidazole;
- Antiegene MB;
- 1,3-Dihydro-2H-Benzimidazole-2-Thione;
- USAF XF – 21;
- USAF EK – 6540;
- NCI – C60980;
- 2-Mercapto Benzimidazole,
- 2-Merkaptobenzimidazole,
- 2-Mercaptobenzoimidazole,
- Vulkanox MB, Nocrac MB
2-Mercaptobenzimidazole, also known as 2-Benzimidazolethiol, is an organosulfur compound that contains a benzimidazole ring with a thiol (-SH) group attached at the second position. This structure gives the compound unique chemical properties, including its role as an intermediate in the synthesis of various pharmaceuticals.
2-Mercaptobenzimidazole is primarily used in the pharmaceutical industry for the synthesis of proton pump inhibitors such as Lansoprazole and Rabeprazole. These medications are used to reduce gastric acid secretion and are commonly prescribed for conditions like gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
Lansoprazole: A proton pump inhibitor (PPI) that reduces stomach acid production and is used to treat and prevent stomach and intestinal ulcers, erosive esophagitis, and other conditions involving excessive stomach acid.
Rabeprazole Another PPI that works similarly to Lansoprazole, used for the treatment of GERD, ulcers, and conditions where reduction of stomach acid is necessary for healing and prevention of acid-related damage.
In summary, 2-Mercaptobenzimidazole's role as a precursor in the synthesis of these drugs highlights its importance in the pharmaceutical industry, particularly in the development of medications that help manage and treat acid-related gastrointestinal conditions.
- Spinning additive used in Nylon tyre cord manufacturer.
- Rubber chemical – Antioxidant for heat resistant rubber articles which must withstand heat, oxygen & steam.
- Also used for white coloured or transparent articles, fabric proofing as it is non-staining.
- Can be used for natural as well as synthetic rubbers.
- Aging inhibitors in electrical insulation. Electroplating Chemical.